Asymmetry between pushing and pulling for crawling cells

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Asymmetry between pushing and pulling for crawling cells.

Eukaryotic cells possess motility mechanisms allowing them not only to self-propel but also to exert forces on obstacles (to push) and to carry cargoes (to pull). To study the inherent asymmetry between active pushing and pulling we model a crawling acto-myosin cell extract as a one-dimensional layer of active gel subjected to external forces. We show that pushing is controlled by protrusion an...

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ژورنال

عنوان ژورنال: Physical Review E

سال: 2013

ISSN: 1539-3755,1550-2376

DOI: 10.1103/physreve.87.022720